A novel sensitive cell-based Love Wave biosensor for marine toxin detection

2017-06-27 Vistors:232

作者Zhang, Xi; Fang, Jiaru; Zou, Ling; .

来源:BIOSENSORS & BIOELECTRONICS  : 77   : 573-579   出版年: MAR 15 2016

A novel HepG2 cell-based biosensor using Love Wave Sensor was developed to implement the real-time and sensitive detection of a diarrheic shellfish poisoning (DSP) toxin, Okadaic acid (OA). Results showed this sensor could monitor the cell attachment process in real time and response signals were related to the initial cell seeding densities. Furthermore, cell-based Love Wave Sensor was treated with OA toxin. This biosensor presented a good performance to various OA concentrations, with a wide linear detection range (10–100 μg/L) and it will be a promising tool for real-time and convenient OA screening.

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