The project, led by Prof. Su Hongye from CSE, won the first prize of Zhejiang Provincial Technological Invention Award. It invented the efficient analysis technology of endogenous fluctuation and optimal suppression of industrial basic control loops and the rapid analysis technology of multi-loop fluctuation, evolution and backtracking. The fluctuation allocation and economic performance evaluation technology of the two-layer predictive control system were invented, and the avoidance mechanism and model mismatch detection were integrated, which solved the landing problem from performance diagnosis to control parameter tuning. This project led the formulation and release of the first international standard ISO 15746 and national standard (GB/T32854) in the field of advanced control and optimization, which have been widely recognized internationally. The achievements have been widely used and promoted in many enterprises such as Juhua with great engineering application value.