The project, directed by Prof. Yang Yang from COSE, was supported by NSFC for Distinguished Young Scholars in 2023. This project is dedicated to advancing high-performance X-ray detectors, targeting three critical challenges within X-ray detection materials and devices: ① mitigating excitation state energy loss, ② manipulating anisotropic carrier transport, and ③ heterogeneous integration of detector arrays ,through the integration of interdisciplinary knowledge in physics, materials science, and information technology. By integrating interdisciplinary knowledge from physics, materials science, and information technology, the goal of the project is to pioneer a state-of-the-art X-ray imaging technology with high sensitivity and spectral discrimination.