作者:Feng Zhe, Chen Siyi, Qian Jun;等
来源:NATURE COMMUNICATIONS 卷:14 期:1 页(号):5017 出版时间: AUG 2023
The limited signal of long-wavelength near-infrared-II (NIR-II, 900–1880 nm) fluorophores, combined with the strong background caused by diffused photons, makes high-contrast deep optical imaging very challenging. We develop bright and long-wavelength NIR-II dyes through novel molecular design and collect the tailing NIR-IIx+NIR-IIb (1400-1700 nm) emission to suppress the imaging background, thereby improving the signal-to-background ratio. This method can open new avenues for the biomedical imaging of deep and highly scattering tissues.