Engineered NIR-II Fluorophores with Ultralong-Distance Molecular Packing for High-Contrast Deep Lesion Identification

2024-06-13 Vistors:10

  作者:Feng Zhe, Chen Siyi, Qian Jun;等

  来源:NATURE COMMUNICATIONS   :14 :1  ()5017  出版时间: AUG 2023

      The limited signal of long-wavelength near-infrared-II (NIR-II, 900–1880 nm) fluorophores, combined with the strong background caused by diffused photons, makes high-contrast deep optical imaging very challenging. We develop bright and long-wavelength NIR-II dyes through novel molecular design and collect the tailing NIR-IIx+NIR-IIb (1400-1700 nm) emission to suppress the imaging background, thereby improving the signal-to-background ratio. This method can open new avenues for the biomedical imaging of deep and highly scattering tissues.

 

 

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